What Are You Looking For?
Enrofloxacin is a new veterinary antimicrobial drug with a broad-spectrum and high antimicrobial effect. It is effective against both gram-positive and gram-negative bacteria as well as mycoplasma. This medication is effective for treating a range of conditions in piglets, including white and yellow diarrhea, oedematous Escherichia coli, paratyphoid fever, porcine pneumonic disease, dengue, mycoplasma pneumonia, atrophic rhinitis, endemic pneumonia, pleuropneumonia, enteritis, diarrhea, uterine inflammation, and streptococcus.
Item NO.:
CAS NO. 93106-60-6Color:
Pale Yellow to Light Beige powder or crystalsPackage:
25 Kg/DrumDescription
Enrofloxacin is an off-white or slightly yellow crystalline needle-like powder that is odourless and tasteless. It is commonly used in its hydrochloride, lactate, or sodium salt forms. The product is soluble in acidic or alkaline conditions, slightly soluble in dimethylformamide and chloroform, and insoluble in water. If stored for a long time, the product's colour may deepen. It is important to store it in a low humidity environment to prevent moisture absorption and caking.
Specification
Item |
Specification |
|
Appearance |
Light yellowish or light orange-yellow, crystalline powder, gradually change to orange red in case of light. |
|
Solubility |
Freely soluble in chloroform, sparing soluble in dimethylformamide, slightly soluble in methanol, very slightly soluble in water; slightly soluble in sodium hydroxide test solution. |
|
Melting point |
221℃~226℃ |
|
HPLC |
The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay. |
|
IR |
The spectrum of sample conforms to that of the reference spectrum. |
|
Tests |
||
Appearance of solution |
Clear;The solution is not more opalescent than reference suspension Ⅰand not more intensely coloured than reference solution Y4 or GY4. |
|
Fluoroquinolonic acid |
Not more than 0.2% |
|
Related substances |
||
Ciprofloxacin |
Not more than 0.5% |
|
Unspecified impurity |
Not more than 0.3% |
|
Total impurities |
Not more than 0.7% |
|
Loss on drying |
Not more than 0.5% |
|
Residue on ignition |
Not more than 0.2% |
|
Heavy metals |
Not more than 0.002% |
|
ASSAY (on dried basis) |
Not less than99.0% of C19H22FN3O3 |
Application
Enrofloxacin and salarfloxacin, difloxacin, difloxacin, ofloxacin, norfloxacin, obafloxacin is often used in veterinary clinical the third generation of fluoroquinolone broad spectrum antibacterial drugs, for ciprofloxacin ethyl compounds, also known as ethyl ciprofloxacin, ethyl, the gram-negative bacteria, gram-positive bacteria and mold form are effective, its antibacterial activity is significantly better than norfloxacin, the effect of mold body is stronger than table, tai mu mycin. This product internal administration, muscle, and subcutaneous injection are easily absorbed, widely distributed in the body, except for the central nervous system, the drug concentration in other tissues is almost all higher than the blood concentration. The active metabolite ciprofloxacin, but the metabolism between species metabolism in animals is large, high in birds, dogs, rabbits and cattle, and low in horses and pigs. Clinical enrofloxacin is mainly used for the treatment of various respiratory system, digestive system, urogenital infections, skin infection and sepsis caused by E. coli, Salmonella, haemophilus, Staphylococcus, streptococcus. It is especially suitable for mixed infections caused by multiple bacteria.
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