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Marbofloxacin is a commonly used bactericide, mainly used for respiratory, digestive, urinary tract and skin infections in cattle, pigs, dogs and cats caused by sensitive bacteria. It can be absorbed well and has low toxic side effects when administered orally and by injection, making it an excellent bactericide.
Item NO.:
CAS NO. 115550-35-1Color:
buff powderPackage:
25 Kg/DrumDescription
Marbofloxacin is a new type of fluoroquinolone antibacterial drug, which can be widely used for its antibacterial effect on Gram-negative and Gram-positive bacteria and mycoplasma by inhibiting bacterial DNA transcriptase and thus inhibiting bacterial growth.
Specification
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Item |
Specification |
|
Appearance |
Light yellow crystalline powder |
|
solubility |
It is slightly dissolved in water,slightly or slightly dissolved in dichloromethane, and extremely slightly dissolved in ethanol(96%) |
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Identification |
Characteristic spectrum IR compared with a standard |
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absorbance |
At 450nm, not over 0.2 |
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Loss on drying |
No more than 0.5% |
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Sulfated ash |
No more than 0.1% |
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Heavy metal |
No more than 20ppm |
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Related substances |
Total impurities not more than 0.5% |
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Assay |
99.0%-101.0%(Dried Substance) |
Application
Marbofloxacin is a fungicide, and its bactericidal activity is concentration-dependent. Sensitive bacteria can die from 20 to 30 rays after exposure. Like other fluoroquinolones, marbofloxacin showed a significant post-antibiotic effect against both Gram-negative and-positive bacteria, active against both the quiescence and the growth phase of bacterial replication. The mechanism of its action is not fully understood, but it is believed to act by inhibiting bacterial DNA gyrase (type II topoisomerase) and preventing DNA supercoiling formation and DNA synthesis. Marboloxacin and other veterinary commercial fluoroquinolones share a similar spectrum of antimicrobial activity. These drugs showed excellent activity against most Gram-negative bacilli and cocci, including most species and strains of Pseudomonas aeruginosa, Klebsiella, Escherichia Escherichia, Enterococcus, Campylobacter, Shigella, Salmonella, Aeromonas, Haemophilus, Proteobacteria, Yersinia, Vibrio, etc. Other prevalent sensitive include Brucella, Chlamydia trachomatis, Staphylococcus (including penicillinase and methicillin-resistant bacteria), Chlamydia, and mycobacteria. Fluoroquinolones have variable activity against most streptococci and are generally not recommended for treating infections of this genus. These drugs are less active against most anaerobes and do not effectively treat anaerobic infections. Due to variation, resistant strains appear, especially Pseudomonas, K. pneumoniae, Acinetobacter and Enterococcus, but it is generally believed that plasmid-mediated resistance rarely occurs.
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