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Nicotinic acid, also known as vitamin B3, is mainly found in animal organs and muscle tissue and also exists in trace amounts in fruits and egg yolks. It is one of the 13 essential vitamins, belonging to the B vitamins, heat-resistant, and capable of sublimation, and is a water-soluble vitamin. Nicotinic acid can be converted into nicotinamide in the human body, involved in the synthesis of coenzyme I and coenzyme II, the body's lipid metabolism, the oxidation of tissue respiration, and the anaerobic decomposition of sugars have an important role.
Item NO.:
CAS NO. 59-67-6Color:
White crystalline or crystalline powderPackage:
25KG/DrumDescription
Nicotinic acid is an indispensable vitamin for the growth of livestock and poultry, possessing a diverse range of physiological functions. It can be utilized as a feed additive to enhance the anti-inflammatory and antioxidant capacities of livestock and poultry, stimulate growth, improve meat quality and carcass characteristics, optimize lactation performance, as well as exert its efficacy in drug administration for treating dyslipidemia, mastitis, and other ailments. Consequently, it enhances the disease resistance of livestock and poultry while reducing mortality rates, ultimately enhancing breeding efficiency.
Specification
|
Item |
Specification |
|
Appearance |
White crystals or crystalline powder |
|
Solubility |
Soluble in boiling water,in boiling alcohol,and in solutions of alkali hydroxides and carbonates; sparingly soluble in water;practically insoluble in ether |
|
Ultraviolet absorption * |
0.46-0.52（A239nm/A263nm） |
|
Infrared absorption * |
Conform to standard spectrum |
|
HPLC Identificaition * |
The retention time of the main peak of the sample is the same as that of the control sample |
|
Assay % |
98.0-102.0 |
|
Chloride % |
≤0.02 |
|
Sulfate % |
≤0.02 |
|
Loss on Drying % |
≤1.0 |
|
Residue on ignition % |
≤0.1 |
|
Any individual unspecified Impurity% |
≤0.05 |
|
Total impurities % |
≤0.20 |
|
Mercury * ppm |
≤0.1 |
|
Lead * ppm |
≤2.0 |
|
Arsenic * ppm |
≤1.0 |
|
Cadmium * ppm |
≤1.0 |
|
Total Plate Count * cfu/g |
≤103 |
|
Yeast & Molds * cfu/g |
≤102 |
|
E. Coli * cfu/g |
Negative |
|
Salmonella * /25g |
Negative |
Application
Nicotinic acid functions as an indispensable coenzyme in the metabolic pathways of carbohydrates, fats, and proteins. It plays a crucial role in facilitating the interconversion between carbohydrates and proteins, as well as the conversion of proteins and carbohydrates into fats. Additionally, it acts as a vital coenzyme for carboxylases by transferring carboxyl groups and fixing carbon dioxide. Moreover, biotin serves as a cofactor for numerous enzymes and acts as a carrier for carboxylation reactions involving carbon dioxide fixation and decarboxylation during carbohydrate metabolism. In animals, biotin participates in essential metabolic processes related to sugars, proteins, and fats through its involvement with coenzymes. Furthermore, biotin is necessary for maintaining proper development of animal skin, hair, hooves, reproduction system functionality, nervous system health; it also enhances feed utilization efficiency and promotes weight gain. Insufficient levels of biotin can result in slow growth rate,reproductive impairments,and various dermatological issues such as dermatitis,hair loss,and skin keratinization.In pigs,it commonly manifests itself through skin ulcers,inflammation of oral mucosa,digestive disorders,muscle cramps,and bleeding on hoof soles.Biotin is primarily used adjunctively to address lesions caused by vitamin H deficiency or malnutrition.The human body requires approximately 100 to 300 micrograms of biotin per day. Raw egg white contains an anti-biotin protein that binds with biotin, rendering it unabsorbable by the digestive tract. This can result in biotin deficiency in animals, leading to symptoms such as decreased appetite, inflammation of ligaments, dandruffy dermatitis, and hair loss. Biotin serves as a coenzyme for numerous enzymes involved in fatty acid and carbohydrate metabolism, facilitates protein synthesis, participates in the metabolism of vitamin B12, folic acid, and pantothenic acid; and promotes urea synthesis and excretion.
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